Melatonin and ALS Prevention



In the musculoskeletal system, there are constant threats in the form of injury, disease, and other disorders. Of these threats, Amyotrphic Lateral Sclerosis (ALS) may be the most terrifying and most harmful in terms of problems in functioning of the musculoskeletal system. Also known as Lou Gehrig’s Disease, ALS has afflicted so many individuals worldwide and the accompanying symptoms are crippling.

ALS is characterized by slowly developing muscle weakness over time to the point where the muscle reach atrophy, or cellular death. When this degenerative process continues to a certain point, the muscles in the respiratory system weaken and eventually collapse, leading to mortality resulting from the inability to breathe.

ALS seems to be on the rise in recent years and the research efforts are expanding in trying to determine the root causes, the physiological basis of the symptoms, and what we can do to combat this terrible condition moving forward.

Recently, research is showing that there is a supplement that can effectively improve outcomes in ALS. A naturally occurring in our bodies called melatonin has been manufactured as a supplement for quite some time. Melatonin is normally used to improve sleep outcomes and help people feel more rested if they are experiencing sleeping problems. However, new research into animal models is showing that melatonin could be quite promising for ALS moving forward.

In various studies involving melatonin and muscle and nerve observation in mice, researchers are beginning to find that melatonin can be a force in preventing the onset of ALS, delaying the degenerative effects on the muscles, and stretching out the amount of time that occurs between the onset of ALS and mortality. The most important part of all of the research being conducted into melatonin’s effects on ALS is the impact of melatonin on the motor neurons that control muscles. Melatonin has the ability to block cellular death in the motor neurons which lengthens the life of individuals with ALS.

There have been numerous awareness efforts along with financial contributions from so many foundations and organizations in an effort to find a cure for ALS and learn more about this terrible condition. This most recent study is a result of that effort and hopefully these types of efforts will continue over time.

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Used under Creative Commons Licensing courtesy of Loren Kerns

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